Mercyhurst University Logo

Darlene Melchitzky

Laboratory Director and Research Associate

Zurn 101

(814) 824-3342

Ms. Melchitzky’s current research focuses on the connections of the mediodorsal thalamic nucleus, including connections with subcortical structures such as the hypothalamus and locus coeruleus as well as connections with the medial temporal, insular and parietal cortices.

Biography: 

Education:

M.S., Neuroscience, University of Pittsburgh, Pittsburgh, PA (1996)
B.A., Chemistry, Mercyhurst College, Erie, PA (1989)

 

Favorite Course in College:

Organic Chemistry

 

Courses Taught:

  • BIO 450 Neurobiology
  • BIO 366 Research Design
  • BIO 466Senior Thesis

 

Select Presentations:

Russell A.L., D.S. Melchitzky, S.L. Erickson, D.A. Lewis (2012) Hypothalamic innervation of the lateral mediodorsal thalamus in macaque monkey: Location of projection neurons. Program No. 8781 Neuroscience Meeting Planner, New Orleans, LA: Society for Neuroscience, 2012. Online.

McCoy, V.L., D.S. Melchitzky, S.L. Erickson, D.A. Lewis (2012) Connections between the medial temporal lobe and the lateral mediodorsal thalamic nucleus in macaque monkey. Program No. 9003 Neuroscience Meeting Planner, New Orleans, LA: Society for Neuroscience, 2012. Online.

Russell, A.L. and D.S. Melchitzky (2012) Hypothalamic innervation of the mediodorsal thalamus in macaque monkey: Location of projection neurons. Program No. 72, Pennsylvania Academy of Sciences, Allentown, PA

 

Select Publications

Lewis DA, Melchitzky DS (2013) Postnatal development of neural circuits in the primate prefrontal cortex. In Principles of Frontal Lobe Function, Oxford University Press, New York, New York.

Eggan SM, Melchitzky DA, Sesack SR, Fish KN, Lewis DA (2010) Relationship of cannabinoid CB1 receptor and cholecystokinin immunoreactivity in monkey dorsolateral prefrontal cortex. Neuroscience, 169:1651-1661

Cruz DA, Weaver C, Lovallo EM, Melchitzky DS, Lewis DA (2009): Selective alterations in postsynaptic markers of chandelier cell inputs to cortical pyramidal neurons in patients with schizophrenia. Neuropsychopharmacology, 34:2112-2124

Melchitzky DS, Lewis DA (2009) Functional neuroanatomy. In HI Kaplan, BJ Sadock, VA Sadock (eds) Comprehensive Textbook of Psychiatry, 9e, Williams & Wilkins, New York, pp. 5-42.

Melchitzky DS, Lewis DA (2009) Chemical neuroanatomy of the primate brain. In AF Shatzberg, CB Nemeroff (eds) American Psychiatric Publishers Textbook of Psychopharmacology, 4e, American Psychiatric Publishing, Inc., Washington, DC., pp. 105-134.

Melchitzky DS, Lewis DA (2008) Dendritic-targeting GABA neurons in monkey prefrontal cortex: Comparison of somatostatin- and calretinin-immunoreactive axon terminals. Synapse, 62:456-465.

Melchitzky, D.S., S.L. Erickson, and D.A. Lewis (2006) Dopamine innervation of the monkey mediodorsal thalamic nucleus: Location of projection neurons and ultrastructural characteristics of axon terminals. Neuroscience, 143:1021-1030.

Melchitzky, D.S., S.M. Eggan, and D.A. Lewis (2005) Synaptic targets of calretinin-containing axon terminals in macaque monkey prefrontal cortex. Neuroscience, 130:185-195.